MK-571

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkbp:alsoKnownAs gptkb:pranlukast
gptkbp:CASNumber 115103-85-0
gptkbp:discoveredBy gptkb:Merck_&_Co.
gptkbp:hasApplication inhibition of multidrug resistance in cancer cells
study of leukotriene pathways
gptkbp:hasMolecularFormula C27H35NO4S
gptkbp:hasRole research tool in pharmacology
gptkbp:hasSMILES CN(C)C(=O)CCCSc1cccc(c1)C=Cc2ccc3cc(Cl)ccc3n2
https://www.w3.org/2000/01/rdf-schema#label MK-571
gptkbp:IUPACName (E)-3-[[[3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid
gptkbp:molecularWeight 469.6 g/mol
gptkbp:PubChem_CID gptkb:CHEMBL123
60714
54713
gptkbp:target gptkb:MRP1_(ABCC1)
gptkb:leukotriene_D4_receptor
gptkbp:usedAs leukotriene D4 receptor antagonist
multidrug resistance protein (MRP) inhibitor
gptkbp:bfsParent gptkb:MRP1
gptkb:multidrug_resistance-associated_protein_1
gptkbp:bfsLayer 6