|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:ERK4
PRKM4
mitogen-activated protein kinase ERK4
|
|
gptkbp:associatedWith
|
cancer (potential role)
|
|
gptkbp:discoveredBy
|
1994
|
|
gptkbp:encodes
|
Mitogen-activated protein kinase 4 protein
|
|
gptkbp:Entrez_Gene_ID
|
5596
ENSG00000163635
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:family
|
gptkb:MAP_kinase_family
|
|
gptkbp:fullName
|
mitogen-activated protein kinase 4
|
|
gptkbp:function
|
signal transduction
serine/threonine protein kinase activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0004674 (protein serine/threonine kinase activity)
GO:0000165 (MAPK cascade)
|
|
gptkbp:hasTranscriptVariant
|
MAPK4-201
MAPK4-202
|
|
gptkbp:HGNC_ID
|
HGNC:6873
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAPK4
|
|
gptkbp:interactsWith
|
gptkb:MAPKAPK5
other MAP kinases
|
|
gptkbp:KEGGID
|
hsa:5596
|
|
gptkbp:length
|
587 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_18
|
|
gptkbp:location
|
18q21.1
|
|
gptkbp:molecularWeight
|
63 kDa
|
|
gptkbp:OMIM
|
600795
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Mapk4
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
cellular response to stress
|
|
gptkbp:PDB
|
1JKK (related structure)
|
|
gptkbp:phosphorylates
|
serine/threonine residues
|
|
gptkbp:Reactome
|
gptkb:R-HSA-5673001
|
|
gptkbp:reference_sequence_protein
|
NP_002738
|
|
gptkbp:RefSeq
|
NM_002747
|
|
gptkbp:regulates
|
cell proliferation
cell survival
differentiation
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P31152
|
|
gptkbp:bfsParent
|
gptkb:R-HSA-5673005
|
|
gptkbp:bfsLayer
|
7
|