Statements (48)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gene
|
| gptkbp:alcoholContent |
gptkb:MAP2
gptkb:MAP1B tubulin |
| gptkbp:associatedWith |
microtubule stabilization
|
| gptkbp:clinicalTrials |
potential therapeutic target
diagnostic marker association with cognitive function association with mood disorders association with neurodevelopmental disorders |
| gptkbp:code |
gptkb:MAP6_protein
|
| gptkbp:community |
transcription factors
epigenetic modifications |
| gptkbp:culturalEvents |
MAP6_in_other_species
|
| gptkbp:diseaseResistance |
gptkb:schizophrenia
bipolar disorder autism spectrum disorder |
| gptkbp:function |
regulation of microtubule dynamics
|
| gptkbp:geneticDiversity |
gptkb:MAP_family
highly conserved across species regulatory elements single nucleotide polymorphisms (SNPs) alternative splicing copy number variations (CNVs) altered neuronal function multiple exons surrounding genes |
| gptkbp:hasFunction |
knockout studies
overexpression studies |
| https://www.w3.org/2000/01/rdf-schema#label |
MAP6 gene
|
| gptkbp:impact |
small molecule inhibitors
gene editing technologies |
| gptkbp:involvedIn |
neuronal development
|
| gptkbp:is_a_route_for |
cell signaling
axon guidance cytoskeleton organization |
| gptkbp:is_evaluated_by |
brain
|
| gptkbp:locatedIn |
human chromosome 3
|
| gptkbp:model |
zebrafish models
mouse_models |
| gptkbp:relatedTo |
neurodegenerative diseases
|
| gptkbp:researchInterest |
gene therapy
biomarker for diseases |
| gptkbp:transportLinks |
gptkb:NCBI_Gene
gptkb:GeneCards Ensembl UCSC Genome Browser OMIM |