Statements (68)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
protein
|
| gptkbp:alcoholContent |
gptkb:MAP_family
coiled-coil regions |
| gptkbp:analyzes |
altered in various neurological disorders
detected in brain tissues |
| gptkbp:animationStudio |
investigated in knockout models
|
| gptkbp:associatedWith |
neurodevelopment
|
| gptkbp:bornIn |
various brain regions
|
| gptkbp:brewingProcess |
cellular response to stress
|
| gptkbp:castMember |
gptkb:MAP1B
|
| gptkbp:clinicalTrials |
neurodegenerative diseases
target for drug development biomarker for brain disorders investigated in clinical settings target for therapeutic intervention |
| gptkbp:community |
regulated by transcription factors
upregulated in response to injury |
| gptkbp:component |
cytoskeleton
|
| gptkbp:culturalEvents |
found in multiple species
|
| gptkbp:expansion |
neurons
|
| gptkbp:fauna |
human
|
| gptkbp:function |
regulates microtubule dynamics
|
| gptkbp:gameMechanics |
modulates cytoskeletal dynamics
|
| gptkbp:geneticDiversity |
gptkb:MAP6
highly conserved chromosome 6 regulated during development affects neuronal function |
| gptkbp:hasFunction |
used in cell culture studies
|
| gptkbp:hasLocation |
axon
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAP6 protein
|
| gptkbp:interactsWith |
protein-protein interaction
tubulin interacts with various cytoskeletal proteins neurofilaments |
| gptkbp:involvedIn |
neuronal differentiation
|
| gptkbp:is_a_route_for |
axon growth
|
| gptkbp:isCelebratedFor |
expressed in neurons
|
| gptkbp:isCharacterizedBy |
characterized in various studies
|
| gptkbp:isOftenUsedIn |
detected_by_Western_blotting
|
| gptkbp:launchSite |
tubulin-binding site
|
| gptkbp:localAttraction |
localized to growth cones
|
| gptkbp:location |
cytoplasm
|
| gptkbp:originalNetwork |
involved in multiple signaling pathways
|
| gptkbp:participatesIn |
involved in Alzheimer's disease
|
| gptkbp:postRetirementCareer |
phosphorylation
|
| gptkbp:primaryFunction |
exhibits multiple isoforms
influences synaptic transmission microtubule stabilization |
| gptkbp:regulates |
involved in neuroinflammation
|
| gptkbp:regulatoryBody |
involved in signaling cascades
part of larger protein complexes |
| gptkbp:regulatoryCompliance |
critical for neuronal health
|
| gptkbp:research |
potential for regenerative medicine
|
| gptkbp:researchFocus |
cognitive function
|
| gptkbp:researchInterest |
immunohistochemistry
neurobiology studies collaborative studies in neuroscience focus on neuroprotective strategies implicated in synaptic plasticity modeling neurodegenerative diseases |
| gptkbp:role |
contributes to neurodegenerative processes
important for neuronal maturation influences cell cycle progression stabilizing microtubules |
| gptkbp:supportRole |
neurite outgrowth
|
| gptkbp:technologyDomain |
microtubule-binding domain
|
| gptkbp:weight |
approximately 70 kDa
|