|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:antibodyTarget
|
immunohistochemistry
|
|
gptkbp:component
|
dendrite
|
|
gptkbp:discoveredBy
|
Shelanski et al.
|
|
gptkbp:discoveredIn
|
1977
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000145348
|
|
gptkbp:expressedIn
|
brain
central nervous system
|
|
gptkbp:fullName
|
Microtubule-associated protein 2
|
|
gptkbp:function
|
stabilizes microtubules
regulates microtubule dynamics
microtubule binding
|
|
gptkbp:gene
|
gptkb:MAP2
|
|
gptkbp:GOProcess
|
neuron projection development
|
|
gptkbp:hasIsoform
|
MAP2A
MAP2B
MAP2C
MAP2D
|
|
gptkbp:HGNC_ID
|
HGNC:6832
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAP2
|
|
gptkbp:interactsWith
|
microtubules
tubulin
|
|
gptkbp:locatedOnChromosome
|
2q34
|
|
gptkbp:location
|
gptkb:cytoplasm
neuronal dendrites
|
|
gptkbp:marking
|
neuronal cells
|
|
gptkbp:molecularWeight
|
280 kDa
|
|
gptkbp:mutationAssociatedWith
|
neurodevelopmental disorders
|
|
gptkbp:OMIM
|
157130
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
1SYF
|
|
gptkbp:phosphorylates
|
regulates function
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:proteinFamily
|
microtubule-associated proteins
|
|
gptkbp:RefSeq
|
NM_002374
|
|
gptkbp:relatedTo
|
gptkb:MAPT
gptkb:MAP4
MAP1A
MAP1B
|
|
gptkbp:role
|
gptkb:synaptic_plasticity
axon guidance
neuronal morphogenesis
|
|
gptkbp:subcellularLocation
|
neuronal cytoskeleton
|
|
gptkbp:UniProtID
|
P11137
|
|
gptkbp:usedIn
|
neuroscience research
|
|
gptkbp:bfsParent
|
gptkb:Microtubule_Associated_Protein
|
|
gptkbp:bfsLayer
|
6
|