Statements (58)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
protein family
|
| gptkbp:diedIn |
development
immune response stress response |
| gptkbp:hasMember |
ERK
JNK p38 MAPK |
| gptkbp:hasRecognition |
biomarkers for disease
target for drug development |
| gptkbp:hasResearchInterest |
therapeutic interventions
diagnostic tools |
| https://www.w3.org/2000/01/rdf-schema#label |
MAP family
|
| gptkbp:includes |
gptkb:MAPKKK
gptkb:MAPKK MAPK |
| gptkbp:interactsWith |
G protein-coupled receptors
receptor tyrosine kinases |
| gptkbp:involvedIn |
apoptosis
cell differentiation cell proliferation cell signaling |
| gptkbp:isAssociatedWith |
metabolic disorders
autoimmune diseases inflammation infectious diseases various diseases |
| gptkbp:isCharacterizedBy |
phosphorylation
kinase activity protein-protein interactions cellular localization regulatory mechanisms |
| gptkbp:isEngagedIn |
small molecules
phosphatases |
| gptkbp:isInvolvedIn |
signal transduction
embryonic development cellular responses to stimuli tissue homeostasis cell fate determination metabolic regulation neurodevelopment |
| gptkbp:isPartOf |
MAPK signaling pathway
cell cycle regulation stress-activated protein kinase pathway |
| gptkbp:isStudiedIn |
neurodegenerative diseases
cancer research cardiovascular diseases |
| gptkbp:isTrainedIn |
monoclonal antibodies
small molecule inhibitors immunotherapies antineoplastic agents |
| gptkbp:isUtilizedFor |
cell growth
cell survival cell migration |
| gptkbp:isVisitedBy |
growth factors
cytokines |
| gptkbp:locatedIn |
eukaryotic_cells
|
| gptkbp:notableFeature |
many species
|
| gptkbp:regulates |
gene expression
|