Lung Squamous Cell Carcinoma
GPTKB entity
Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:cancer
|
| gptkbp:alternativeName |
Lung SCC
Squamous cell carcinoma of the lung |
| gptkbp:associatedWith |
Paraneoplastic syndromes
|
| gptkbp:firstDescribed |
Described in early 20th century
|
| gptkbp:hasDiagnosticMethod |
gptkb:CT_scan
gptkb:Bronchoscopy PET scan Biopsy |
| gptkbp:hasGenderPrevalence |
More common in males
|
| gptkbp:hasMetastasisSite |
gptkb:bone
gptkb:Brain Liver Adrenal gland |
| gptkbp:hasPrimarySite |
Lung
|
| gptkbp:hasScreeningMethod |
Low-dose CT scan
|
| gptkbp:hasTypicalPatient |
Older adults
Current or former smokers |
| gptkbp:histology |
Keratinization
Intercellular bridges |
| https://www.w3.org/2000/01/rdf-schema#label |
Lung Squamous Cell Carcinoma
|
| gptkbp:ICD-10_code |
C34
|
| gptkbp:incidence |
Decreasing in developed countries
|
| gptkbp:location |
Central bronchi
|
| gptkbp:marking |
gptkb:p63
p40 CK5/6 |
| gptkbp:mutationAssociatedWith |
gptkb:TP53_mutation
PIK3CA mutation CDKN2A mutation |
| gptkbp:prevalence |
Second most common type of lung cancer
|
| gptkbp:prognosis |
Stage at diagnosis
Generally poor Performance status Presence of metastasis |
| gptkbp:riskFactor |
Smoking
Exposure to asbestos Exposure to radon gas |
| gptkbp:stageName |
gptkb:TNM
|
| gptkbp:subspecies |
gptkb:Non-Small_Cell_Lung_Cancer
|
| gptkbp:symptom |
Cough
Hemoptysis Shortness of breath Chest pain |
| gptkbp:treatment |
radiation therapy
Surgery immunotherapy Chemotherapy |
| gptkbp:bfsParent |
gptkb:LSCC
|
| gptkbp:bfsLayer |
6
|