Statements (32)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor cell surface receptor |
gptkbp:alternativeName |
gptkb:LHR
LHCGR Lutropin-choriogonadotropin receptor |
gptkbp:associatedWith |
infertility
precocious puberty Leydig cell hypoplasia |
gptkbp:binds |
gptkb:luteinizing_hormone
chorionic gonadotropin |
gptkbp:encodedBy |
LHCGR gene
|
gptkbp:Entrez_Gene_ID |
3973
|
gptkbp:expressedIn |
gptkb:Leydig_cells
granulosa cells theca cells |
gptkbp:foundIn |
gptkb:placenta
gptkb:testis |
gptkbp:function |
mediates effects of LH and hCG
regulates reproductive processes stimulates steroidogenesis |
gptkbp:HGNC_ID |
6586
|
https://www.w3.org/2000/01/rdf-schema#label |
LHCG receptor
|
gptkbp:locatedOnChromosome |
2p21
|
gptkbp:OMIM |
152790
|
gptkbp:transmembraneDomains |
yes
|
gptkbp:type |
activates adenylate cyclase
increases cAMP |
gptkbp:UniProtID |
P22888
|
gptkbp:bfsParent |
gptkb:human_chorionic_gonadotropin
gptkb:choriogonadotropin_alfa |
gptkbp:bfsLayer |
7
|