Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:cell_surface_receptor gptkb:G_protein-coupled_receptor |
| gptkbp:alternativeName |
gptkb:LHR
LHCGR Lutropin-choriogonadotropin receptor |
| gptkbp:associatedWith |
infertility
precocious puberty Leydig cell hypoplasia |
| gptkbp:binds |
gptkb:luteinizing_hormone
chorionic gonadotropin |
| gptkbp:encodedBy |
LHCGR gene
|
| gptkbp:Entrez_Gene_ID |
3973
|
| gptkbp:expressedIn |
gptkb:Leydig_cells
granulosa cells theca cells |
| gptkbp:foundIn |
gptkb:placenta
gptkb:testis |
| gptkbp:function |
mediates effects of LH and hCG
regulates reproductive processes stimulates steroidogenesis |
| gptkbp:HGNC_ID |
6586
|
| gptkbp:locatedOnChromosome |
2p21
|
| gptkbp:OMIM |
152790
|
| gptkbp:transmembraneDomains |
yes
|
| gptkbp:type |
activates adenylate cyclase
increases cAMP |
| gptkbp:UniProtID |
P22888
|
| gptkbp:bfsParent |
gptkb:human_chorionic_gonadotropin
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
LHCG receptor
|