LDH-1

GPTKB entity

Statements (21)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:EC_number 1.1.1.27
gptkbp:electrophoresisMobility fastest among LDH isoenzymes
gptkbp:foundIn gptkb:kidney
brain
red blood cells
heart muscle
skeletal muscle (lesser extent)
gptkbp:fullName Lactate dehydrogenase 1
gptkbp:function catalyzes conversion of lactate to pyruvate
gptkbp:gene gptkb:LDHB_gene
https://www.w3.org/2000/01/rdf-schema#label LDH-1
gptkbp:isoenzymeOf lactate dehydrogenase (LDH)
gptkbp:molecularWeight ~140 kDa
gptkbp:significance elevated in myocardial infarction
used in diagnosis of heart attack
gptkbp:subunit gptkb:H_(heart)_subunit
tetramer of H (heart) subunits
gptkbp:tissue_specificity predominant in aerobic tissues
gptkbp:bfsParent gptkb:LDH
gptkbp:bfsLayer 6