|
gptkbp:instanceOf
|
amino acid transporter
|
|
gptkbp:biosynthesized_from
|
gptkb:ATP
gptkb:glutamine
gptkb:phosphoribosyl-ATP
gptkb:phosphoribosyl_pyrophosphate
glutamate
|
|
gptkbp:CASNumber
|
71-00-1
|
|
gptkbp:category
|
proteinogenic amino acid
alpha-amino acid
basic amino acid
essential amino acid
glucogenic amino acid
imidazole-containing compound
|
|
gptkbp:chemicalFormula
|
C6H9N3O2
|
|
gptkbp:chirality
|
L-form
|
|
gptkbp:codons
|
gptkb:CAC
gptkb:CAU
|
|
gptkbp:discoveredBy
|
gptkb:Albrecht_Kossel
|
|
gptkbp:discoveredIn
|
1896
|
|
gptkbp:essential_amino_acid
|
true
|
|
gptkbp:found_in_protein
|
true
|
|
gptkbp:foundIn
|
gptkb:fish
gptkb:meat
eggs
grains
dairy products
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
L-histidine
|
|
gptkbp:isomerOf
|
gptkb:D-histidine
|
|
gptkbp:IUPACName
|
gptkb:(S)-2-Amino-3-(1H-imidazol-4-yl)propanoic_acid
|
|
gptkbp:meltingPoint
|
287°C (decomposes)
|
|
gptkbp:metabolism_location
|
gptkb:kidney
liver
|
|
gptkbp:molecularWeight
|
155.15 g/mol
|
|
gptkbp:pKa
|
6.0
|
|
gptkbp:predecessor
|
gptkb:carnosine
gptkb:histamine
gptkb:urocanic_acid
gptkb:anserine
|
|
gptkbp:role_in_proteins
|
metal ion binding
buffering
active site of enzymes
proton shuttle
|
|
gptkbp:side_chain
|
imidazole
|
|
gptkbp:solubility
|
41.6 g/L (20°C)
|
|
gptkbp:usedFor
|
allergies
ulcers
rheumatoid arthritis
|
|
gptkbp:bfsParent
|
gptkb:Gardasil
|
|
gptkbp:bfsLayer
|
5
|