| 
                                    
                                        gptkbp:instanceOf
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:vaccine
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:administeredBy
                                    
                                 | 
                                
                                    
                                        
                                            
                                            adults 18 years and older
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:alsoKnownAs
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Oxford–AstraZeneca_COVID-19_vaccine
                                        
                                         
                                    
                                        
                                            gptkb:Vaxzevria
                                        
                                         
                                    
                                        
                                            gptkb:Covishield
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:approvedBy
                                    
                                 | 
                                
                                    
                                        
                                            
                                            December 2020
                                        
                                        
                                         
                                    
                                        
                                            
                                            over 180 countries
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:category
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:COVID-19_vaccines
                                        
                                         
                                    
                                        
                                            
                                            2020 introductions
                                        
                                        
                                         
                                    
                                        
                                            
                                            AstraZeneca products
                                        
                                        
                                         
                                    
                                        
                                            
                                            Viral vector vaccines
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:clinicalTrialPhase
                                    
                                 | 
                                
                                    
                                        
                                            
                                            conducted in UK, Brazil, South Africa
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:compatibleWith
                                    
                                 | 
                                
                                    
                                        
                                            
                                            United States (as of 2024)
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:contains
                                    
                                 | 
                                
                                    
                                        
                                            
                                            genetic material encoding SARS-CoV-2 spike protein
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:contraindication
                                    
                                 | 
                                
                                    
                                        
                                            
                                            severe allergic reaction to previous dose
                                        
                                        
                                         
                                    
                                        
                                            
                                            known hypersensitivity to ingredients
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:developedBy
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:University_of_Oxford
                                        
                                         
                                    
                                        
                                            gptkb:AstraZeneca
                                        
                                         
                                    
                                        
                                            gptkb:Serum_Institute_of_India
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:dosingSchedule
                                    
                                 | 
                                
                                    
                                        
                                            
                                            two doses, 4–12 weeks apart
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:effect
                                    
                                 | 
                                
                                    
                                        
                                            
                                            ~70% (varies by study and dosing interval)
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:emergencyServices
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:India
                                        
                                         
                                    
                                        
                                            gptkb:World_Health_Organization
                                        
                                         
                                    
                                        
                                            gptkb:UK_Medicines_and_Healthcare_products_Regulatory_Agency
                                        
                                         
                                    
                                        
                                            gptkb:European_Medicines_Agency
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:mainIngredient
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:L-histidine
                                        
                                         
                                    
                                        
                                            gptkb:disodium_edetate_dihydrate
                                        
                                         
                                    
                                        
                                            gptkb:polysorbate_80
                                        
                                         
                                    
                                        
                                            
                                            sodium chloride
                                        
                                        
                                         
                                    
                                        
                                            
                                            ethanol
                                        
                                        
                                         
                                    
                                        
                                            
                                            sucrose
                                        
                                        
                                         
                                    
                                        
                                            
                                            water for injections
                                        
                                        
                                         
                                    
                                        
                                            
                                            magnesium chloride hexahydrate
                                        
                                        
                                         
                                    
                                        
                                            
                                            L-histidine hydrochloride monohydrate
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:manufacturer
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:SK_Bioscience
                                        
                                         
                                    
                                        
                                            gptkb:AstraZeneca
                                        
                                         
                                    
                                        
                                            gptkb:Serum_Institute_of_India
                                        
                                         
                                    
                                        
                                            gptkb:R-Pharm
                                        
                                         
                                    
                                        
                                            gptkb:Siam_Bioscience
                                        
                                         
                                    
                                        
                                            gptkb:Fiocruz
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:routeOfAdministration
                                    
                                 | 
                                
                                    
                                        
                                            
                                            intramuscular injection
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:sideEffect
                                    
                                 | 
                                
                                    
                                        
                                            
                                            fatigue
                                        
                                        
                                         
                                    
                                        
                                            
                                            headache
                                        
                                        
                                         
                                    
                                        
                                            
                                            injection site pain
                                        
                                        
                                         
                                    
                                        
                                            
                                            rare blood clotting events
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:storage
                                    
                                 | 
                                
                                    
                                        
                                            
                                            2–8°C
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:target
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:COVID-19
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:trialSponsor
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Saudi_Arabian_government
                                        
                                         
                                    
                                        
                                            gptkb:Ugandan_government
                                        
                                         
                                    
                                        
                                            gptkb:Rwandan_government
                                        
                                         
                                    
                                        
                                            gptkb:COVAX
                                        
                                         
                                    
                                        
                                            gptkb:Colombian_government
                                        
                                         
                                    
                                        
                                            gptkb:Gavi
                                        
                                         
                                    
                                        
                                            gptkb:Qatari_government
                                        
                                         
                                    
                                        
                                            gptkb:NIHR
                                        
                                         
                                    
                                        
                                            gptkb:Chilean_government
                                        
                                         
                                    
                                        
                                            gptkb:European_Parliament
                                        
                                         
                                    
                                        
                                            gptkb:European_Union
                                        
                                         
                                    
                                        
                                            gptkb:Government_of_India
                                        
                                         
                                    
                                        
                                            gptkb:Parliament_of_the_United_Kingdom
                                        
                                         
                                    
                                        
                                            gptkb:University_of_Oxford
                                        
                                         
                                    
                                        
                                            gptkb:WHO
                                        
                                         
                                    
                                        
                                            gptkb:Afghan_government
                                        
                                         
                                    
                                        
                                            gptkb:Philippine_government
                                        
                                         
                                    
                                        
                                            gptkb:Yemeni_government
                                        
                                         
                                    
                                        
                                            gptkb:South_Korean_government
                                        
                                         
                                    
                                        
                                            gptkb:Palestinian_government
                                        
                                         
                                    
                                        
                                            gptkb:Omani_government
                                        
                                         
                                    
                                        
                                            gptkb:UK_Research_and_Innovation
                                        
                                         
                                    
                                        
                                            gptkb:Iranian_government
                                        
                                         
                                    
                                        
                                            gptkb:Japanese_government
                                        
                                         
                                    
                                        
                                            gptkb:Burundian_government
                                        
                                         
                                    
                                        
                                            gptkb:Congolese_government
                                        
                                         
                                    
                                        
                                            gptkb:CEPI
                                        
                                         
                                    
                                        
                                            gptkb:AstraZeneca
                                        
                                         
                                    
                                        
                                            gptkb:Bill_&_Melinda_Gates_Foundation
                                        
                                         
                                    
                                        
                                            gptkb:Indonesian_government
                                        
                                         
                                    
                                        
                                            gptkb:Mexican
                                        
                                         
                                    
                                        
                                            gptkb:Wellcome_Trust
                                        
                                         
                                    
                                        
                                            gptkb:Turkish_government
                                        
                                         
                                    
                                        
                                            gptkb:Vietnamese_government
                                        
                                         
                                    
                                        
                                            gptkb:BARDA
                                        
                                         
                                    
                                        
                                            gptkb:Zimbabwean_government
                                        
                                         
                                    
                                        
                                            gptkb:Egyptian_government
                                        
                                         
                                    
                                        
                                            gptkb:Namibian_government
                                        
                                         
                                    
                                        
                                            gptkb:South_African_government
                                        
                                         
                                    
                                        
                                            gptkb:Bahraini_government
                                        
                                         
                                    
                                        
                                            gptkb:Kuwaiti_government
                                        
                                         
                                    
                                        
                                            gptkb:Lebanese_government
                                        
                                         
                                    
                                        
                                            gptkb:Malaysian_government
                                        
                                         
                                    
                                        
                                            gptkb:Singaporean_government
                                        
                                         
                                    
                                        
                                            gptkb:Pakistani_government
                                        
                                         
                                    
                                        
                                            gptkb:Brazilian_government
                                        
                                         
                                    
                                        
                                            gptkb:Kenyan_government
                                        
                                         
                                    
                                        
                                            gptkb:Tanzanian_government
                                        
                                         
                                    
                                        
                                            gptkb:Bangladeshi_government
                                        
                                         
                                    
                                        
                                            gptkb:Syrian_government
                                        
                                         
                                    
                                        
                                            gptkb:Angolan_government
                                        
                                         
                                    
                                        
                                            gptkb:Sudanese_government
                                        
                                         
                                    
                                        
                                            gptkb:Serum_Institute_of_India
                                        
                                         
                                    
                                        
                                            gptkb:BARDA_(US)
                                        
                                         
                                    
                                        
                                            gptkb:Botswanan_government
                                        
                                         
                                    
                                        
                                            gptkb:National_Institutes_of_Health_(US)
                                        
                                         
                                    
                                        
                                            gptkb:United_Arab_Emirates_government
                                        
                                         
                                    
                                        
                                            gptkb:Ethiopian_government
                                        
                                         
                                    
                                        
                                            gptkb:Jordanian_government
                                        
                                         
                                    
                                        
                                            gptkb:Sri_Lankan_government
                                        
                                         
                                    
                                        
                                            gptkb:Coalition_for_Epidemic_Preparedness_Innovations
                                        
                                         
                                    
                                        
                                            gptkb:Mozambican_government
                                        
                                         
                                    
                                        
                                            gptkb:Nepalese_government
                                        
                                         
                                    
                                        
                                            
                                            Iraqi government
                                        
                                        
                                         
                                    
                                        
                                            
                                            Argentinian government
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:type
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:viral_vector_vaccine
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:vectorFor
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:chimpanzee_adenovirus_(ChAdOx1)
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:WHO_EUL
                                    
                                 | 
                                
                                    
                                        
                                            
                                            February 2021
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsParent
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:AstraZeneca_COVID-19_vaccine
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsLayer
                                    
                                 | 
                                
                                    
                                        
                                            
                                            6
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        https://www.w3.org/2000/01/rdf-schema#label
                                    
                                 | 
                                
                                    
                                        
                                            
                                            AZD1222
                                        
                                        
                                         
                                    
                                 |