Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:FKLF
gptkb:TIEG2 |
| gptkbp:associatedWith |
MODY7 (Maturity Onset Diabetes of the Young type 7)
|
| gptkbp:contains |
zinc finger domains
|
| gptkbp:encodes |
KLF11 protein
|
| gptkbp:Entrez_Gene_ID |
16592 (mouse)
8463 (human) ENSG00000171316 (human) ENSMUSG00000022101 (mouse) |
| gptkbp:expressedIn |
gptkb:cancer
gptkb:kidney brain liver pancreas |
| gptkbp:fullName |
gptkb:Kruppel-like_factor_11
|
| gptkbp:function |
transcription factor
|
| gptkbp:HGNC_ID |
HGNC:6342
|
| https://www.w3.org/2000/01/rdf-schema#label |
Klf11
|
| gptkbp:locatedOnChromosome |
2 (mouse)
2p25 (human) |
| gptkbp:mutationAssociatedWith |
gptkb:diabetes
|
| gptkbp:OMIM |
604928
|
| gptkbp:organism |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:proteinFamily |
gptkb:Kruppel-like_factors
|
| gptkbp:regulates |
apoptosis
differentiation lipid metabolism cellular senescence cell growth glucose metabolism inflammation gene silencing DNA methylation cell cycle neuronal differentiation tumor suppression oxidative stress response insulin secretion fibrosis epithelial-mesenchymal transition TGF-beta signaling chromatin remodeling SMAD7 expression hepatocyte proliferation insulin gene expression histone acetylation beta cell function |
| gptkbp:UniProtID |
Q9Y484 (human)
|
| gptkbp:bfsParent |
gptkb:KLF11
|
| gptkbp:bfsLayer |
8
|