|
gptkbp:instanceOf
|
immune response
cell surface receptor
lymphocyte
|
|
gptkbp:activatedBy
|
antigen-presenting cells
|
|
gptkbp:alsoKnownAs
|
gptkb:CD8+_T_cell
cytotoxic T cell
|
|
gptkbp:canBeEngineeredAs
|
gptkb:CAR-T_cell
|
|
gptkbp:developsIn
|
gptkb:thymus
|
|
gptkbp:discoveredBy
|
gptkb:Peter_Doherty
gptkb:Rolf_Zinkernagel
|
|
gptkbp:discoveredIn
|
1970s
|
|
gptkbp:expressedIn
|
gptkb:CD8_glycoprotein
|
|
gptkbp:foundIn
|
blood
lymphoid tissues
|
|
gptkbp:function
|
kills cancer cells
kills damaged cells
kills virus-infected cells
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Killer T Cell
|
|
gptkbp:inducedBy
|
apoptosis in target cells
|
|
gptkbp:marking
|
gptkb:CD8
gptkb:T_cell_receptor_(TCR)
|
|
gptkbp:measures
|
flow cytometry
|
|
gptkbp:partOf
|
gptkb:adaptive_immune_system
|
|
gptkbp:proliferatesInResponseTo
|
antigen stimulation
|
|
gptkbp:recognizedBy
|
antigen presented by MHC class I molecules
|
|
gptkbp:relatedTo
|
helper T cell
memory T cell
regulatory T cell
|
|
gptkbp:role
|
immunotherapy
autoimmune diseases
transplant rejection
viral clearance
|
|
gptkbp:secretes
|
gptkb:granzymes
gptkb:perforin
granulysin
|
|
gptkbp:target
|
immunosuppressive drugs
|
|
gptkbp:bfsParent
|
gptkb:Cells_at_Work!
|
|
gptkbp:bfsLayer
|
4
|