|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:Prostate-specific_antigen
Kallikrein-related peptidase 3
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:benign_prostatic_hyperplasia
prostate cancer
|
|
gptkbp:biologicalProcess
|
proteolysis
seminal plasma protein degradation
|
|
gptkbp:discoveredBy
|
gptkb:T._Ming_Chu
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:encodes
|
gptkb:prostate-specific_antigen
|
|
gptkbp:Entrez_Gene_ID
|
354
ENSG00000142515
|
|
gptkbp:expressedIn
|
gptkb:prostate
|
|
gptkbp:function
|
serine protease activity
liquefaction of seminal coagulum
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:6364
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KLK3 gene
|
|
gptkbp:length
|
261 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
19q13.33
|
|
gptkbp:molecularWeight
|
28.4 kDa
|
|
gptkbp:OMIM
|
176820
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Klk1b21
|
|
gptkbp:product
|
gptkb:protein
contains trypsin-like serine protease domain
|
|
gptkbp:proteinFamily
|
kallikrein gene family
|
|
gptkbp:RefSeq
|
NM_001648
|
|
gptkbp:regulates
|
androgen-regulated
|
|
gptkbp:significance
|
biomarker for prostate cancer
|
|
gptkbp:UniProtID
|
P07288
|
|
gptkbp:bfsParent
|
gptkb:prostate-specific_antigen
gptkb:Prostate-specific_antigen
|
|
gptkbp:bfsLayer
|
7
|