KIT-positive gastrointestinal stromal tumors
GPTKB entity
Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gastrointestinal_stromal_tumor
|
gptkbp:diagnosedBy |
immunohistochemistry
molecular genetic testing |
gptkbp:firstDescribed |
1983
|
gptkbp:hasBiomarker |
KIT (CD117)
|
gptkbp:hasCellOfOrigin |
gptkb:interstitial_cells_of_Cajal
|
gptkbp:hasLocation |
gastrointestinal tract
|
gptkbp:hasSubgroup |
gastrointestinal stromal tumors
|
https://www.w3.org/2000/01/rdf-schema#label |
KIT-positive gastrointestinal stromal tumors
|
gptkbp:ICD-10_code |
C49.A
|
gptkbp:location |
gptkb:small_intestine
stomach |
gptkbp:mutationAssociatedWith |
gptkb:KIT_gene
PDGFRA gene (rarely) |
gptkbp:occurredIn |
colon
esophagus rectum mesentery omentum |
gptkbp:prognosis |
variable
tumor size tumor location mitotic rate |
gptkbp:synonym |
CD117-positive GIST
KIT+ GIST |
gptkbp:treatment |
gptkb:imatinib
gptkb:regorafenib gptkb:sunitinib surgery |
gptkbp:bfsParent |
gptkb:CHEMBL472
|
gptkbp:bfsLayer |
7
|