KIT-positive gastrointestinal stromal tumors

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:gastrointestinal_stromal_tumor
gptkbp:diagnosedBy immunohistochemistry
molecular genetic testing
gptkbp:firstDescribed 1983
gptkbp:hasBiomarker KIT (CD117)
gptkbp:hasCellOfOrigin gptkb:interstitial_cells_of_Cajal
gptkbp:hasLocation gastrointestinal tract
gptkbp:hasSubgroup gastrointestinal stromal tumors
https://www.w3.org/2000/01/rdf-schema#label KIT-positive gastrointestinal stromal tumors
gptkbp:ICD-10_code C49.A
gptkbp:location gptkb:small_intestine
stomach
gptkbp:mutationAssociatedWith gptkb:KIT_gene
PDGFRA gene (rarely)
gptkbp:occurredIn colon
esophagus
rectum
mesentery
omentum
gptkbp:prognosis variable
tumor size
tumor location
mitotic rate
gptkbp:synonym CD117-positive GIST
KIT+ GIST
gptkbp:treatment gptkb:imatinib
gptkb:regorafenib
gptkb:sunitinib
surgery
gptkbp:bfsParent gptkb:CHEMBL472
gptkbp:bfsLayer 7