KIT-positive gastrointestinal stromal tumors
GPTKB entity
Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gastrointestinal_stromal_tumor
|
| gptkbp:diagnosedBy |
immunohistochemistry
molecular genetic testing |
| gptkbp:firstDescribed |
1983
|
| gptkbp:hasBiomarker |
KIT (CD117)
|
| gptkbp:hasCellOfOrigin |
gptkb:interstitial_cells_of_Cajal
|
| gptkbp:hasLocation |
gastrointestinal tract
|
| gptkbp:hasSubgroup |
gastrointestinal stromal tumors
|
| gptkbp:ICD-10_code |
C49.A
|
| gptkbp:location |
gptkb:small_intestine
stomach |
| gptkbp:mutationAssociatedWith |
gptkb:KIT_gene
PDGFRA gene (rarely) |
| gptkbp:occurredIn |
colon
esophagus rectum mesentery omentum |
| gptkbp:prognosis |
variable
tumor size tumor location mitotic rate |
| gptkbp:synonym |
CD117-positive GIST
KIT+ GIST |
| gptkbp:treatment |
gptkb:imatinib
gptkb:regorafenib gptkb:sunitinib surgery |
| gptkbp:bfsParent |
gptkb:CHEMBL472
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
KIT-positive gastrointestinal stromal tumors
|