KIR-K5

GPTKB entity

Statements (13)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName MIR2
gptkbp:encodedBy gptkb:Kaposi's_sarcoma-associated_herpesvirus
gptkbp:function E3 ubiquitin ligase
downregulates B7-2 (CD86)
downregulates ICAM-1
downregulates MHC class I molecules
https://www.w3.org/2000/01/rdf-schema#label KIR-K5
gptkbp:mechanismOfAction ubiquitinates target proteins for degradation
gptkbp:roleInPathogenesis immune evasion by Kaposi's sarcoma-associated herpesvirus
gptkbp:species gptkb:human_herpesvirus_8
gptkbp:bfsParent gptkb:Killer_cell_immunoglobulin-like_receptor_2DS1
gptkbp:bfsLayer 8