Statements (13)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
MIR2
|
| gptkbp:encodedBy |
gptkb:Kaposi's_sarcoma-associated_herpesvirus
|
| gptkbp:function |
gptkb:E3_ubiquitin_ligase
downregulates B7-2 (CD86) downregulates ICAM-1 downregulates MHC class I molecules |
| gptkbp:mechanismOfAction |
ubiquitinates target proteins for degradation
|
| gptkbp:roleInPathogenesis |
immune evasion by Kaposi's sarcoma-associated herpesvirus
|
| gptkbp:species |
gptkb:human_herpesvirus_8
|
| gptkbp:bfsParent |
gptkb:Killer_cell_immunoglobulin-like_receptor_2DS1
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
KIR-K5
|