KIM-1

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:HAVCR1
gptkb:Kidney_Injury_Molecule-1
gptkbp:associatedWith gptkb:ischemia-reperfusion_injury
renal cell carcinoma
gptkbp:cleavedForm soluble KIM-1 in urine
gptkbp:discoveredBy gptkb:Joseph_V._Bonventre
gptkbp:domain Ig-like domain
mucin domain
gptkbp:encodedBy gptkb:HAVCR1_gene
gptkbp:expressedIn renal proximal tubule epithelial cells
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function biomarker for kidney injury
mediates phagocytosis of apoptotic cells
gptkbp:gene gptkb:HAVCR1
gptkbp:HGNC_ID 4815
https://www.w3.org/2000/01/rdf-schema#label KIM-1
gptkbp:locatedOnChromosome gptkb:chromosome_5
5q33.3
gptkbp:location gptkb:cell_membrane
gptkbp:medicalUse monitoring nephrotoxicity
predicting kidney disease progression
gptkbp:molecularWeight ~38 kDa
gptkbp:OMIM 604980
gptkbp:regulates upregulated by kidney injury
gptkbp:species gptkb:human
gptkbp:structure type I transmembrane glycoprotein
gptkbp:UniProtID gptkb:Q96D42
gptkbp:upregulatedBy chronic kidney disease
acute kidney injury
gptkbp:usedAs urinary biomarker
gptkbp:usedFor diagnosis of kidney injury
gptkbp:bfsParent gptkb:Microchess
gptkbp:bfsLayer 6