|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:HAVCR1
gptkb:Kidney_Injury_Molecule-1
|
|
gptkbp:associatedWith
|
gptkb:renal_cell_carcinoma
gptkb:ischemia-reperfusion_injury
|
|
gptkbp:cleavedForm
|
soluble KIM-1 in urine
|
|
gptkbp:discoveredBy
|
gptkb:Joseph_V._Bonventre
|
|
gptkbp:domain
|
Ig-like domain
mucin domain
|
|
gptkbp:encodedBy
|
gptkb:HAVCR1_gene
|
|
gptkbp:expressedIn
|
renal proximal tubule epithelial cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
biomarker for kidney injury
mediates phagocytosis of apoptotic cells
|
|
gptkbp:gene
|
gptkb:HAVCR1
|
|
gptkbp:HGNC_ID
|
4815
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
5q33.3
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:medicalUse
|
monitoring nephrotoxicity
predicting kidney disease progression
|
|
gptkbp:molecularWeight
|
~38 kDa
|
|
gptkbp:OMIM
|
604980
|
|
gptkbp:regulates
|
upregulated by kidney injury
|
|
gptkbp:species
|
gptkb:human
|
|
gptkbp:structure
|
type I transmembrane glycoprotein
|
|
gptkbp:UniProtID
|
gptkb:Q96D42
|
|
gptkbp:upregulatedBy
|
gptkb:acute_kidney_injury
chronic kidney disease
|
|
gptkbp:usedAs
|
urinary biomarker
|
|
gptkbp:usedFor
|
diagnosis of kidney injury
|
|
gptkbp:bfsParent
|
gptkb:Microchess
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KIM-1
|