Statements (19)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:associatedWith |
cell growth
immune response hematopoiesis |
| gptkbp:cause |
transcriptional activation
STAT dimerization STAT phosphorylation STAT nuclear translocation |
| gptkbp:dysregulationLinkedTo |
gptkb:cancer
autoimmune diseases |
| https://www.w3.org/2000/01/rdf-schema#label |
JAK-STAT pathway activation
|
| gptkbp:involves |
gptkb:STAT_proteins
gptkb:JAK_kinases |
| gptkbp:launched |
receptor dimerization
|
| gptkbp:occurredIn |
cell cytoplasm
|
| gptkbp:result |
gene expression regulation
|
| gptkbp:triggeredBy |
cytokine binding
|
| gptkbp:bfsParent |
gptkb:JAK2_mutation
|
| gptkbp:bfsLayer |
6
|