Inducible T-cell co-stimulator
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
gptkb:CD278
|
| gptkbp:associatedWith |
autoimmune diseases
immunodeficiency |
| gptkbp:biologicalProcess |
receptor activity
immune system process T cell costimulation |
| gptkbp:cellularComponent |
gptkb:plasma_membrane
|
| gptkbp:encodedBy |
gptkb:ICOS_gene
|
| gptkbp:Entrez_Gene_ID |
29851
|
| gptkbp:expressedIn |
activated T cells
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
costimulatory molecule for T-cell activation
|
| gptkbp:HGNC_ID |
16983
|
| https://www.w3.org/2000/01/rdf-schema#label |
Inducible T-cell co-stimulator
|
| gptkbp:ligand |
ICOS ligand (ICOSL)
|
| gptkbp:locatedOnChromosome |
chromosome 2
|
| gptkbp:memberOf |
gptkb:CD28_family
|
| gptkbp:OMIM |
604558
|
| gptkbp:role |
immune response
germinal center formation T-cell proliferation cytokine secretion |
| gptkbp:symbol |
gptkb:ICOS
|
| gptkbp:UniProtID |
O75144
|
| gptkbp:bfsParent |
gptkb:CD278
|
| gptkbp:bfsLayer |
8
|