Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:monoclonal_antibody
|
gptkbp:binds |
antigens
|
gptkbp:canActivate |
complement system
|
gptkbp:discoveredBy |
gptkb:Tomio_Tada
|
gptkbp:foundIn |
blood
lymph fluid |
gptkbp:fullName |
gptkb:Immunoglobulin_M
|
gptkbp:function |
first antibody produced in response to infection
|
gptkbp:halfLife |
about 5 days
|
gptkbp:heavyChainType |
mu chain
|
https://www.w3.org/2000/01/rdf-schema#label |
IgM
|
gptkbp:isotypeOf |
immune response
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_14_(IGHM_gene_in_humans)
|
gptkbp:measures |
gptkb:ELISA
|
gptkbp:molecularWeight |
~900 kDa
|
gptkbp:presentIn |
all vertebrates except jawless fish
|
gptkbp:producedBy |
gptkb:B_cells
|
gptkbp:role |
primary immune response
|
gptkbp:significance |
marker for recent infection
|
gptkbp:structure |
pentamer
|
gptkbp:usedIn |
diagnosis of acute infections
|
gptkbp:bfsParent |
gptkb:anti-B_antibody
|
gptkbp:bfsLayer |
6
|