Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:monoclonal_antibody
|
| gptkbp:abbreviation |
gptkb:IgM
|
| gptkbp:discoveredBy |
gptkb:Oswald_Avery
gptkb:Michael_Heidelberger |
| gptkbp:discoveredIn |
1937
|
| gptkbp:encodedBy |
gptkb:IGHM_gene
|
| gptkbp:foundIn |
blood
lymph fluid |
| gptkbp:function |
activates complement system
first antibody produced in response to infection |
| gptkbp:halfLife |
about 5 days
|
| gptkbp:hasHeavyChainType |
mu chain
|
| https://www.w3.org/2000/01/rdf-schema#label |
Immunoglobulin M
|
| gptkbp:measures |
serology
|
| gptkbp:molecularWeight |
~900 kDa
|
| gptkbp:presentIn |
gptkb:fish
birds amphibians mammals reptiles |
| gptkbp:producedBy |
gptkb:B_cells
|
| gptkbp:role |
primary immune response
|
| gptkbp:significance |
marker of recent infection
used in diagnosis of infectious diseases |
| gptkbp:structure |
pentamer
|
| gptkbp:subclassOf |
immune response
|
| gptkbp:bfsParent |
gptkb:IgM
gptkb:IGM gptkb:Repeat_SARS-CoV-2_Nucleic_acid_and_Immunoglobulin_G/Immunoglobulin_M_Detection |
| gptkbp:bfsLayer |
7
|