IMP-type metallo-beta-lactamase
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:cofactor |
zinc
|
| gptkbp:detects |
PCR
phenotypic tests |
| gptkbp:enzymeClassification |
metallo-beta-lactamase
|
| gptkbp:firstDescribed |
gptkb:Japan
1991 |
| gptkbp:foundIn |
Gram-negative bacteria
|
| gptkbp:function |
hydrolyzes beta-lactam antibiotics
|
| gptkbp:gene |
blaIMP
|
| https://www.w3.org/2000/01/rdf-schema#label |
IMP-type metallo-beta-lactamase
|
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
gptkb:sulbactam gptkb:EDTA tazobactam |
| gptkbp:resistantTo |
carbapenem antibiotics
antibiotic inactivation |
| gptkbp:significance |
multidrug resistance
|
| gptkbp:spreadTo |
plasmids
integrons |
| gptkbp:subclassOf |
class B beta-lactamase
|
| gptkbp:bfsParent |
gptkb:antimicrobial_resistance_gene_IMP
|
| gptkbp:bfsLayer |
8
|