Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
cytokine
|
gptkbp:alsoKnownAs |
Interleukin-22
|
gptkbp:discoveredIn |
2000
|
gptkbp:Entrez_Gene_ID |
50616
ENSG00000127318 |
gptkbp:function |
induction of antimicrobial proteins
maintenance of epithelial barrier promotion of tissue repair regulation of immune responses |
gptkbp:gene |
IL22
IL22 gene |
https://www.w3.org/2000/01/rdf-schema#label |
IL 22
|
gptkbp:involvedIn |
autoimmune diseases
inflammatory diseases psoriasis inflammatory bowel disease liver regeneration host defense against bacteria |
gptkbp:locatedOnChromosome |
gptkb:12q15
|
gptkbp:producedBy |
gptkb:natural_killer_cells
gptkb:gamma_delta_T_cells gptkb:innate_lymphoid_cells T helper 17 cells |
gptkbp:receptorComponent |
IL-10R2
IL-22R1 |
gptkbp:recipient |
IL-22 receptor
|
gptkbp:species |
gptkb:Homo_sapiens
|
gptkbp:targetTissue |
gptkb:hepatocytes
gptkb:keratinocytes epithelial cells |
gptkbp:UniProtID |
Q9GZX6
|
gptkbp:bfsParent |
gptkb:IL_59
|
gptkbp:bfsLayer |
8
|