capillary leak syndrome

GPTKB entity

Statements (39)
Predicate Object
gptkbp:instanceOf medical condition
gptkbp:affects capillaries
gptkbp:alsoKnownAs Clarkson's disease
systemic capillary leak syndrome
gptkbp:canBeFatal true
gptkbp:causedBy leakage of plasma from capillaries into surrounding tissues
gptkbp:characterizedBy edema
hypoalbuminemia
hemoconcentration
recurrent episodes of severe hypotension
gptkbp:complication immunotherapy
stem cell transplantation
gptkbp:diagnosedBy laboratory tests
clinical evaluation
exclusion of other causes
gptkbp:firstDescribed 1960
Dr. Bayard Clarkson
https://www.w3.org/2000/01/rdf-schema#label capillary leak syndrome
gptkbp:ICD-10_code R60.1
gptkbp:prognosis variable
gptkbp:rareDisease true
gptkbp:symptom shock
swelling
organ failure
low blood pressure
gptkbp:treatment gptkb:theophylline
albumin
immunoglobulins
vasopressors
intravenous fluids
terbutaline
gptkbp:triggeredBy gptkb:cancer
certain medications
autoimmune diseases
infections
monoclonal gammopathy
gptkbp:bfsParent gptkb:Interleukin-2
gptkb:Proleukin
gptkbp:bfsLayer 6