Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
IL-12R-beta-2
interleukin 12 receptor, beta 2 |
| gptkbp:associatedWith |
autoimmune diseases
susceptibility to tuberculosis susceptibility to leprosy |
| gptkbp:encodes |
Interleukin-12 receptor subunit beta-2
|
| gptkbp:Entrez_Gene_ID |
3595
ENSG00000162594 |
| gptkbp:expressedIn |
immune cells
|
| gptkbp:function |
forms part of the receptor for interleukin-12
involved in Th1 cell differentiation |
| gptkbp:HGNC_ID |
HGNC:5971
|
| gptkbp:locatedOnChromosome |
1p31.3
|
| gptkbp:OMIM |
601642
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:pathway |
gptkb:JAK-STAT_signaling_pathway
|
| gptkbp:product |
IL12RB2 protein
|
| gptkbp:regulates |
upregulated by interferon-gamma
|
| gptkbp:UniProtID |
Q99665
|
| gptkbp:bfsParent |
gptkb:IL-12_receptor
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL12RB2 gene
|