Statements (58)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:vaccine
|
| gptkbp:associated_with |
autoimmune diseases
viral infections |
| gptkbp:discovered_by |
2000s
|
| gptkbp:enhances |
antibody production
C D8+ T cell responses |
| gptkbp:established |
apoptosis in B cells
|
| gptkbp:function |
regulates immune responses
|
| gptkbp:has_role |
chronic inflammation
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL-21
|
| gptkbp:influences |
B cell activation
immune tolerance immune cell activation cytokine production T cell differentiation T cell memory NK cell activity immune checkpoint regulation T cell exhaustion immune system homeostasis immune cell migration Treg cell function cytokine signaling pathways cytokine network memory T cell formation Th1 cell responses autoantibody production immune response to tumors |
| gptkbp:is_involved_in |
gptkb:healthcare_organization
gptkb:cystic_fibrosis gptkb:systemic_lupus_erythematosus gptkb:psychologist gptkb:rheumatoid_arthritis neuroinflammation cardiovascular diseases sepsis chronic kidney disease psoriasis transplant rejection chronic obstructive pulmonary disease T cell proliferation tumor immunity cancer immunotherapy vaccine responses chronic viral infections allergic responses neoplastic diseases B cell differentiation Th17 cell differentiation HIV infection response |
| gptkbp:is_vulnerable_to |
IL-21 receptor
|
| gptkbp:produced_by |
gptkb:T_cells
NKT cells follicular helper T cells |
| gptkbp:targets |
gptkb:T_cells
B cells |
| gptkbp:bfsParent |
gptkb:T-helper_17_cells
|
| gptkbp:bfsLayer |
6
|