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gptkbp:instance_of
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gptkb:Genetics
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gptkbp:advocacy
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gptkb:Cystic_Fibrosis_Foundation
gptkb:CF_Canada
gptkb:Cystic_Fibrosis_Trust
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gptkbp:affects
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digestive system
lungs
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gptkbp:associated_with
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gptkb:diabetes
infertility in males
pancreatic insufficiency
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gptkbp:caused_by
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mutation in the CFTR gene
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gptkbp:complications
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respiratory failure
sinusitis
liver disease
lung damage
osteoporosis
gastroesophageal reflux disease (GERD)
intestinal blockages
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gptkbp:diagnosis
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genetic testing
sweat test
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gptkbp:famous_person
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gptkb:Megan_Mc_Carthy
gptkb:Molly_Mc_Carthy
gptkb:Megan_Mc_Glover
gptkb:Paul_Quarrington
Megan O' Neill
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gptkbp:first_described_by
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gptkb:Dorothy_Anderson
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https://www.w3.org/2000/01/rdf-schema#label
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cystic fibrosis
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gptkbp:inherits_from
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autosomal recessive
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gptkbp:is_common_in
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gptkb:African_Americans
gptkb:Native_American_culture
gptkb:Ashkenazi_Jews
Caucasians
Hispanics
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gptkbp:lifespan
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varies by severity
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gptkbp:prevalence
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1 in 3,500 births in the United States
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gptkbp:research_focus
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gptkb:gene_therapy
improving quality of life
new medications
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gptkbp:screenings
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newborn screening
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gptkbp:symptoms
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frequent lung infections
persistent cough
shortness of breath
wheezing
poor growth
salty skin
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gptkbp:treatment
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gptkb:CFTR_modulators
chest physiotherapy
enzyme supplements
inhaled medications
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gptkbp:bfsParent
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gptkb:Sangamo_Therapeutics
gptkb:Vertex_Pharmaceuticals
gptkb:CRISPR-Cas9
gptkb:CRISPR_technology
gptkb:Canadian_Cystic_Fibrosis_Foundation
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gptkbp:bfsLayer
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4
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