Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:bfsLayer |
7
|
| gptkbp:bfsParent |
gptkb:Iκ_B_proteins
|
| gptkbp:associated_with |
cancer progression
|
| gptkbp:clinical_trial |
ubiquitination
|
| gptkbp:code |
NFKBIA gene
|
| gptkbp:discovered_by |
human cells
|
| gptkbp:established |
phosphorylation
NF-κ B translocation to nucleus apoptosis in certain contexts pro-inflammatory cytokines |
| gptkbp:function |
inhibits NF-κ B signaling
|
| https://www.w3.org/2000/01/rdf-schema#label |
Iκ Bα
|
| gptkbp:interacts_with |
NF-κ B
|
| gptkbp:is_aimed_at |
anti-inflammatory drugs
|
| gptkbp:is_associated_with |
chronic inflammation
|
| gptkbp:is_essential_for |
immune system function
|
| gptkbp:is_involved_in |
gptkb:psychologist
cell cycle regulation cell differentiation cell proliferation cellular homeostasis cellular stress response wound healing neuroinflammation stress response fibrosis cardiovascular diseases cell signaling pathways tumorigenesis cellular aging immune tolerance angiogenesis inflammatory response tissue repair neuroprotection metastasis metabolic regulation cell survival pathways cellular responses to stress cytokine signaling response to pathogens apoptotic signaling |
| gptkbp:is_linked_to |
autoimmune diseases
|
| gptkbp:is_part_of |
transcriptional regulation
NF-κ B signaling pathway |
| gptkbp:is_represented_in |
gptkb:smartphone
various tissues |
| gptkbp:location |
cytoplasm
|
| gptkbp:metabolism |
gptkb:IKK_complex
|
| gptkbp:produced_by |
Iκ Bα gene
|
| gptkbp:promoter |
NFKBIA
|
| gptkbp:regulates |
Iκ B kinase (IKK)
NF-κ B pathway |
| gptkbp:related_to |
gptkb:Iκ_B_proteins
|
| gptkbp:role |
regulator of immune response
|
| gptkbp:weight |
approximately 37 k Da
|