Statements (51)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
histone |
gptkbp:component |
nucleosome
|
gptkbp:conservedIn |
highly conserved
|
gptkbp:discoveredBy |
19th century
|
gptkbp:encodedBy |
HIST1H4A gene
HIST1H4B gene HIST1H4C gene HIST1H4D gene HIST1H4E gene HIST1H4F gene HIST1H4H gene HIST1H4I gene HIST1H4J gene HIST1H4K gene HIST2H4A gene HIST2H4B gene HIST3H4 gene |
gptkbp:form |
H3-H4 tetramer
|
gptkbp:formsComplexWith |
gptkb:Histone_H3
Histone H2A Histone H2B |
gptkbp:foundIn |
eukaryotes
|
gptkbp:function |
chromatin structure
DNA packaging |
https://www.w3.org/2000/01/rdf-schema#label |
Histone H4
|
gptkbp:interactsWith |
gptkb:gene
histone chaperones |
gptkbp:length |
102 amino acids
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_6_(human)
|
gptkbp:molecularWeight |
11.3 kDa
|
gptkbp:orthologIn |
Drosophila histone H4
mouse histone H4 yeast histone H4 |
gptkbp:PDB |
1KX5
|
gptkbp:postTranslationalModification |
phosphorylation
methylation ubiquitination acetylation |
gptkbp:requires |
cell viability
chromosome stability |
gptkbp:subjectOf |
epigenetic regulation
gene expression regulation chromatin remodeling histone code hypothesis |
gptkbp:subunit |
histone octamer
|
gptkbp:symbol |
H4
|
gptkbp:UniProtID |
P62805
|
gptkbp:bfsParent |
gptkb:P62834
gptkb:P62826 |
gptkbp:bfsLayer |
7
|