Hereditary Breast and Ovarian Cancer syndrome
GPTKB entity
Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
|
| gptkbp:abbreviation |
gptkb:HBOC
|
| gptkbp:associatedWith |
gptkb:BRCA1
gptkb:BRCA2 |
| gptkbp:diagnosedBy |
genetic testing
|
| gptkbp:firstDescribed |
1990s
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hereditary Breast and Ovarian Cancer syndrome
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:managedBy |
risk-reducing surgery
chemoprevention increased surveillance |
| gptkbp:notableInPopulation |
Ashkenazi Jewish
|
| gptkbp:OMIM |
604370
|
| gptkbp:prevalence |
1 in 400 to 1 in 800 individuals
|
| gptkbp:riskFactor |
gptkb:cancer
pancreatic cancer prostate cancer |
| gptkbp:symptom |
early-onset breast cancer
multiple family members with breast or ovarian cancer |
| gptkbp:bfsParent |
gptkb:hereditary_breast_cancer
|
| gptkbp:bfsLayer |
7
|