Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:alsoKnownAs |
Buchwald-Hartwig coupling
|
| gptkbp:application |
organic synthesis
pharmaceutical synthesis |
| gptkbp:basisFor |
potassium tert-butoxide
sodium tert-butoxide |
| gptkbp:catalyzes |
palladium complex
|
| gptkbp:category |
transition metal catalysis
C-N bond formation |
| gptkbp:developedBy |
gptkb:John_F._Hartwig
gptkb:Stephen_L._Buchwald |
| gptkbp:firstReported |
1994
|
| https://www.w3.org/2000/01/rdf-schema#label |
Buchwald-Hartwig amination
|
| gptkbp:involves |
amphetamine
aryl halide |
| gptkbp:ligand |
phosphine ligand
|
| gptkbp:mechanismOfAction |
oxidative addition
reductive elimination deprotonation amine coordination |
| gptkbp:product |
aryl amine
|
| gptkbp:relatedTo |
gptkb:Ullmann_reaction
gptkb:Suzuki_coupling |
| gptkbp:solvent |
toluene
dioxane |
| gptkbp:type |
cross-coupling reaction
|
| gptkbp:bfsParent |
gptkb:Hartwig-Buchwald_coupling
|
| gptkbp:bfsLayer |
7
|