Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:catalyzes |
endonuclease activity
|
gptkbp:contains |
asparagine residues
histidine (second) residues histidine residues |
gptkbp:firstDescribed |
1990s
|
gptkbp:foundIn |
gptkb:Cas9_protein
restriction enzymes CRISPR-associated nucleases bacterial proteins bacteriophage proteins homing endonucleases nucleases |
gptkbp:function |
genome editing
DNA cleavage site-specific DNA cleavage |
https://www.w3.org/2000/01/rdf-schema#label |
HNH motif
|
gptkbp:InterPro |
IPR003615
|
gptkbp:metalIonCofactor |
zinc
magnesium |
gptkbp:namedAfter |
histidine-asparagine-histidine
|
gptkbp:prosite |
PS50841
|
gptkbp:proteinFamily |
PF01844
|
gptkbp:relatedTo |
His-Me finger
|
gptkbp:sequence |
H-N-H
|
gptkbp:structure |
beta-beta-alpha-metal fold
|
gptkbp:bfsParent |
gptkb:HNH
|
gptkbp:bfsLayer |
7
|