HNH motif

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:catalyzes endonuclease activity
gptkbp:contains asparagine residues
histidine (second) residues
histidine residues
gptkbp:firstDescribed 1990s
gptkbp:foundIn gptkb:Cas9_protein
restriction enzymes
CRISPR-associated nucleases
bacterial proteins
bacteriophage proteins
homing endonucleases
nucleases
gptkbp:function genome editing
DNA cleavage
site-specific DNA cleavage
https://www.w3.org/2000/01/rdf-schema#label HNH motif
gptkbp:InterPro IPR003615
gptkbp:metalIonCofactor zinc
magnesium
gptkbp:namedAfter histidine-asparagine-histidine
gptkbp:prosite PS50841
gptkbp:proteinFamily PF01844
gptkbp:relatedTo His-Me finger
gptkbp:sequence H-N-H
gptkbp:structure beta-beta-alpha-metal fold
gptkbp:bfsParent gptkb:HNH
gptkbp:bfsLayer 7