|
gptkbp:instanceOf
|
gptkb:major_histocompatibility_complex
|
|
gptkbp:associatedWith
|
autoimmune diseases
transplant rejection
|
|
gptkbp:composedOf
|
gptkb:HLA-DR_alpha_chain
HLA-DR beta chain
|
|
gptkbp:discoveredIn
|
1970s
|
|
gptkbp:encodes
|
HLA-DR protein
|
|
gptkbp:expressedIn
|
gptkb:B_cells
dendritic cells
macrophages
antigen-presenting cells
|
|
gptkbp:function
|
antigen presentation
|
|
gptkbp:hasAllele
|
gptkb:HLA-DR4
HLA-DR1
HLA-DR10
HLA-DR11
HLA-DR12
HLA-DR13
HLA-DR14
HLA-DR15
HLA-DR16
HLA-DR17
HLA-DR18
HLA-DR2
HLA-DR3
HLA-DR5
HLA-DR51
HLA-DR52
HLA-DR53
HLA-DR6
HLA-DR7
HLA-DR8
HLA-DR9
|
|
gptkbp:hasPolymorphism
|
true
|
|
gptkbp:importantFor
|
gptkb:immune_response
|
|
gptkbp:involves
|
gptkb:systemic_lupus_erythematosus
Graves' disease
multiple sclerosis
type 1 diabetes
rheumatoid arthritis
celiac disease
|
|
gptkbp:locatedIn
|
gptkb:chromosome_6
|
|
gptkbp:locusTag
|
gptkb:6p21.3
|
|
gptkbp:partOf
|
gptkb:human_leukocyte_antigen_system
|
|
gptkbp:recognizedBy
|
gptkb:CD4+_T_cells
|
|
gptkbp:relatedTo
|
HLA-DP antigen system
HLA-DQ antigen system
|
|
gptkbp:usedIn
|
organ transplantation
tissue typing
|
|
gptkbp:bfsParent
|
gptkb:DR8
gptkb:DR9
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HLA-DR antigen system
|