Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:major_histocompatibility_complex
|
| gptkbp:associatedWith |
autoimmune diseases
transplant rejection |
| gptkbp:composedOf |
gptkb:HLA-DR_alpha_chain
HLA-DR beta chain |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodes |
HLA-DR protein
|
| gptkbp:expressedIn |
gptkb:B_cells
dendritic cells macrophages antigen-presenting cells |
| gptkbp:function |
antigen presentation
|
| gptkbp:hasAllele |
gptkb:HLA-DR4
HLA-DR1 HLA-DR10 HLA-DR11 HLA-DR12 HLA-DR13 HLA-DR14 HLA-DR15 HLA-DR16 HLA-DR17 HLA-DR18 HLA-DR2 HLA-DR3 HLA-DR5 HLA-DR51 HLA-DR52 HLA-DR53 HLA-DR6 HLA-DR7 HLA-DR8 HLA-DR9 |
| gptkbp:hasPolymorphism |
true
|
| https://www.w3.org/2000/01/rdf-schema#label |
HLA-DR antigen system
|
| gptkbp:importantFor |
immune response
|
| gptkbp:involves |
gptkb:systemic_lupus_erythematosus
Graves' disease multiple sclerosis type 1 diabetes rheumatoid arthritis celiac disease |
| gptkbp:locatedIn |
gptkb:chromosome_6
|
| gptkbp:locusTag |
gptkb:6p21.3
|
| gptkbp:partOf |
gptkb:human_leukocyte_antigen_system
|
| gptkbp:recognizedBy |
gptkb:CD4+_T_cells
|
| gptkbp:relatedTo |
HLA-DP antigen system
HLA-DQ antigen system |
| gptkbp:usedIn |
organ transplantation
tissue typing |
| gptkbp:bfsParent |
gptkb:DR8
gptkb:DR9 |
| gptkbp:bfsLayer |
7
|