Gossypol

GPTKB entity

Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:Dragon
gptkb:chemical_compound
polyphenol
gptkbp:CASNumber 303-45-7
gptkbp:chemicalFormula C30H30O8
gptkbp:color yellow
gptkbp:contains_functional_group phenol
aldehyde
methyl
isopropyl
gptkbp:discoveredIn cottonseed oil
gptkbp:effect antiviral activity
antitumor activity
antifertility agent
toxic to non-ruminant animals
gptkbp:foundIn cottonseed
cotton plants
gptkbp:has_stereochemistry (+)-gossypol
(–)-gossypol
gptkbp:hasAbsorptionMaxima 365 nm
254 nm
https://www.w3.org/2000/01/rdf-schema#label Gossypol
gptkbp:inhibitedBy gptkb:Bcl-2_family_proteins
gptkb:lactate_dehydrogenase
gptkbp:IUPACName 2,2'-bis(8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)
gptkbp:meltingPoint 210–220 °C
gptkbp:molecularWeight 518.55 g/mol
gptkbp:producedBy Gossypium species
gptkbp:PubChem_CID gptkb:CHEMBL418
3503
CHEBI:42145
gptkbp:sideEffect hypokalemia
irreversible infertility (in some cases)
gptkbp:solubility slightly soluble in water
soluble in ether
soluble in acetone
soluble in chloroform
gptkbp:stateAtRoomTemperature gptkb:stone
gptkbp:studiedBy gptkb:cancer
contraceptive development
gptkbp:toxicity toxic to humans in high doses
gptkbp:UNII 8MDF5V39QO
gptkbp:usedAs male contraceptive (experimental)
gptkbp:bfsParent gptkb:Cottonseed
gptkbp:bfsLayer 8