Gn RH agonists

GPTKB entity

Statements (55)
Predicate Object
gptkbp:instance_of gptkb:Planned_Parenthood
gptkbp:administered_by gptkb:Skin
injection
gptkbp:affects bone density loss
metabolic changes
testosterone levels
pituitary gland
cardiovascular risks
estrogen levels
gptkbp:clinical_trial Phase II
Phase III
Phase I
gptkbp:contraindication pregnancy
breastfeeding
hypersensitivity to the drug
gptkbp:developed_by gptkb:1980s
gptkbp:example gptkb:goserelin
gptkb:leuprolide
gptkb:triptorelin
nafarelin
gptkbp:formulation gptkb:Skin
injectable solution
implant
https://www.w3.org/2000/01/rdf-schema#label Gn RH agonists
gptkbp:interacts_with anticoagulants
hormonal contraceptives
other hormone therapies
gptkbp:invention patented
generic available
gptkbp:marketed_as gptkb:Lupron
gptkb:Zoladex
gptkb:Trelstar
Synarel
gptkbp:mechanism_of_action suppressing gonadotropin release
gptkbp:patient_population adult men
adult women
children with precocious puberty
gptkbp:regulatory_compliance FDA approved
EMA approved
gptkbp:research_focus gptkb:cancer_treatment
reproductive health
fertility preservation
endometriosis management
gptkbp:route_of_administration subcutaneous
intranasal
intramuscular
gptkbp:side_effect osteoporosis
mood changes
hot flashes
decreased libido
gptkbp:used_for treating endometriosis
treating precocious puberty
treating hormone-sensitive cancers
gptkbp:bfsParent gptkb:Endometriosis
gptkbp:bfsLayer 4