Zoladex

GPTKB entity

Properties (49)
Predicate Object
gptkbp:instanceOf medication
gptkbp:activeDuring gptkb:goserelin
gptkbp:brand gptkb:Zoladex
gptkbp:chemicalFormula C64H86N18O13S
gptkbp:clinicalTrials Phase II
Phase III
Phase I
gptkbp:contraindication pregnancy
hypersensitivity_to_goserelin
gptkbp:dosageForm depot injection
gptkbp:drugInterdiction excreted in urine
subcutaneous absorption
metabolized in liver
gonadotropin-releasing hormone agonist
gptkbp:duration 28 days
gptkbp:endOfLife 2 to 4 hours
gptkbp:firstAppearance 1989
gptkbp:formFactor implant
https://www.w3.org/2000/01/rdf-schema#label Zoladex
gptkbp:legalStatus prescription only
gptkbp:mandates endometriosis
advanced breast cancer
central precocious puberty
uterine fibroids
advanced prostate cancer
gptkbp:manufacturer gptkb:AstraZeneca
gptkbp:marketedAs gptkb:Australia
gptkb:Canada
gptkb:United_Kingdom
gptkb:United_States
gptkbp:operates_in L02AE01
gptkbp:patentExpiration 2010
2015
2020
2025
gptkbp:route subcutaneous injection
gptkbp:sideEffect fatigue
headache
nausea
weight gain
injection site reactions
mood changes
hot flashes
decreased libido
gptkbp:usedFor breast cancer
prostate cancer
endometriosis
precocious puberty
gptkbp:weight 1439.67 g/mol