|
gptkbp:instance_of
|
gptkb:pharmaceuticals
|
|
gptkbp:available_on
|
generic version
|
|
gptkbp:brand
|
gptkb:Lupron
gptkb:Lupron_Depot-PED
gptkb:Lupron_Depot-3_Month
|
|
gptkbp:class
|
gptkb:Hirogen
|
|
gptkbp:clinical_trial
|
Phase III
|
|
gptkbp:contraindication
|
pregnancy
breastfeeding
|
|
gptkbp:dosage_form
|
subcutaneous injection
|
|
gptkbp:duration
|
varies by condition
typically several months
|
|
gptkbp:effective_date
|
gptkb:1985
|
|
gptkbp:formulation
|
injectable solution
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Lupron
|
|
gptkbp:indication
|
uterine fibroids
hormone-sensitive cancers
|
|
gptkbp:ingredients
|
gptkb:leuprolide
|
|
gptkbp:interacts_with
|
anticoagulants
hormonal contraceptives
antidiabetic medications
|
|
gptkbp:invention
|
2025
|
|
gptkbp:is_monitored_by
|
bone density
hormone levels
blood glucose levels
|
|
gptkbp:lifespan
|
3 hours
|
|
gptkbp:manufacturer
|
gptkb:Abb_Vie
|
|
gptkbp:marketed_as
|
gptkb:Canada
gptkb:European_Union
gptkb:United_States
|
|
gptkbp:mechanism_of_action
|
suppresses gonadotropin release
|
|
gptkbp:requires
|
gptkb:true
|
|
gptkbp:rounds
|
urine
|
|
gptkbp:route_of_administration
|
injection
|
|
gptkbp:side_effect
|
gptkb:anemia
fatigue
nausea
cardiovascular issues
insomnia
weight gain
headaches
osteoporosis
mood changes
hot flashes
|
|
gptkbp:storage
|
room temperature
protected from light
|
|
gptkbp:trade
|
gptkb:Lupron_Injection
gptkb:Lupron_Depot
|
|
gptkbp:used_for
|
gptkb:Oncology
gptkb:endometriosis
precocious puberty
|
|
gptkbp:bfsParent
|
gptkb:Gn_RH_agonists
gptkb:Zoladex
|
|
gptkbp:bfsLayer
|
5
|