|
gptkbp:instance_of
|
gptkb:protein
|
|
gptkbp:bfsLayer
|
5
|
|
gptkbp:bfsParent
|
gptkb:Gn_RH_agonists
gptkb:Trelstar
|
|
gptkbp:activities
|
gptkb:item
|
|
gptkbp:appointed_by
|
injection
|
|
gptkbp:approves
|
gptkb:legislation
gptkb:1986
gptkb:Australia
gptkb:United_States
gptkb:Native_American_tribe
|
|
gptkbp:brand
|
gptkb:Decapeptyl
gptkb:Trelstar
|
|
gptkbp:clinical_trial
|
Phase II trials for endometriosis
Phase III trials for precocious puberty
Phase III trials for prostate cancer
|
|
gptkbp:contraindication
|
pregnancy
breastfeeding
hypersensitivity to triptorelin
|
|
gptkbp:developed_by
|
gptkb:Debiopharm
gptkb:Ipsen
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
triptorelin
|
|
gptkbp:ingredients
|
C64 H86 N18 O13 S
|
|
gptkbp:is_atype_of
|
L02 A E01
|
|
gptkbp:is_available_on
|
generic version
|
|
gptkbp:is_used_for
|
gptkb:healthcare_organization
gptkb:endometriosis
precocious puberty
|
|
gptkbp:manager
|
subcutaneous
intramuscular
|
|
gptkbp:marketed_as
|
gptkb:Decapeptyl_SR
gptkb:Triptorelin_Pamoate
gptkb:Trelstar_Depot
|
|
gptkbp:pharmacokinetics
|
excreted in urine
metabolized in the liver
inhibits gonadotropin release
reduces testosterone levels
half-life of approximately 3 hours
reduces estrogen levels
|
|
gptkbp:related_to
|
hormonal therapy
gonadotropin-releasing hormone
Gn RH analogs
androgen deprivation therapy
|
|
gptkbp:side_effect
|
fatigue
headache
nausea
weight gain
mood changes
hot flashes
decreased libido
|
|
gptkbp:social_structure
|
gptkb:protein
|
|
gptkbp:storage
|
store at room temperature
protect from light
do not freeze
|
|
gptkbp:type_of
|
57773-63-4
|