Statements (24)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:discoveredBy |
1990s
|
gptkbp:effect |
activates potassium channels
inhibits calcium channels inhibits neurotransmitter release |
gptkbp:encodedBy |
gptkb:GABBR1_gene
gptkb:GABBR2_gene |
gptkbp:enemyOf |
gptkb:baclofen
gptkb:phaclofen |
gptkbp:function |
mediates inhibitory neurotransmission
|
https://www.w3.org/2000/01/rdf-schema#label |
GABA-B receptor family
|
gptkbp:involves |
addiction
epilepsy anxiety spasticity |
gptkbp:ligand |
gptkb:gamma-aminobutyric_acid_(GABA)
|
gptkbp:location |
central nervous system
|
gptkbp:member |
GABA-B1 receptor
GABA-B2 receptor |
gptkbp:receptor_type |
metabotropic
|
gptkbp:signal_transduction |
G-protein coupled
|
gptkbp:subclassOf |
gptkb:G_protein-coupled_receptor
|
gptkbp:bfsParent |
gptkb:GABBR1_gene
|
gptkbp:bfsLayer |
7
|