Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme_cofactor |
| gptkbp:activatedBy |
gptkb:thrombin
|
| gptkbp:biologicalProcess |
cofactor activity
|
| gptkbp:complex_catalyzes |
activation of Factor X
|
| gptkbp:component |
tenase complex
|
| gptkbp:deficiencyCauses |
gptkb:hemophilia_A
|
| gptkbp:EC_number |
3.4.21.5
|
| gptkbp:formsComplexWith |
gptkb:Factor_IXa
|
| gptkbp:function |
cofactor in blood coagulation
|
| gptkbp:gene |
gptkb:F8
|
| gptkbp:inhibitedBy |
activated protein C
|
| gptkbp:is_activated_form_of |
Factor VIII
|
| gptkbp:location |
blood plasma
|
| gptkbp:participatedIn |
intrinsic pathway of coagulation
|
| gptkbp:significance |
target for hemophilia A therapy
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
P00451
|
| gptkbp:bfsParent |
gptkb:Factor_IXa
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Factor VIIIa
|