Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:anticoagulant |
| gptkbp:activatedBy |
gptkb:Factor_VIIa
|
| gptkbp:alternativeName |
proconvertin
stable factor |
| gptkbp:cofactor |
gptkb:vitamin_A
|
| gptkbp:deficiencyCauses |
bleeding disorders
|
| gptkbp:discoveredIn |
1940s
|
| gptkbp:EC_number |
3.4.21.21
|
| gptkbp:encodedBy |
F7 gene
|
| gptkbp:foundIn |
human blood plasma
|
| gptkbp:function |
initiates extrinsic pathway of blood coagulation
|
| gptkbp:hasTherapeuticUse |
recombinant Factor VIIa for hemophilia
|
| https://www.w3.org/2000/01/rdf-schema#label |
Factor VII
|
| gptkbp:interactsWith |
tissue factor
|
| gptkbp:locatedOnChromosome |
chromosome 13q34
|
| gptkbp:measures |
prothrombin time (PT) test
|
| gptkbp:molecularWeight |
approximately 50 kDa
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:synthesisType |
liver
|
| gptkbp:usedIn |
diagnosis of coagulation disorders
|
| gptkbp:bfsParent |
gptkb:Factor_VIIa
|
| gptkbp:bfsLayer |
7
|