FTO alpha-ketoglutarate dependent dioxygenase
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
Fat mass and obesity-associated protein
|
| gptkbp:associatedWith |
obesity
|
| gptkbp:biologicalProcess |
oxidoreductase activity
RNA modification |
| gptkbp:cofactor |
gptkb:alpha-ketoglutarate
Fe(II) |
| gptkbp:EC_number |
1.14.11.2
|
| gptkbp:encodedBy |
FTO gene
|
| gptkbp:expressedIn |
brain
adipose tissue |
| gptkbp:function |
demethylation of nucleic acids
|
| https://www.w3.org/2000/01/rdf-schema#label |
FTO alpha-ketoglutarate dependent dioxygenase
|
| gptkbp:locatedOnChromosome |
gptkb:16q12.2
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:mutationAssociatedWith |
increased body mass index
|
| gptkbp:OMIM |
610966
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
3LFM
|
| gptkbp:UniProtID |
Q9C0B1
|
| gptkbp:bfsParent |
gptkb:ENSG00000113525
|
| gptkbp:bfsLayer |
7
|