Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
protein filament
|
| gptkbp:alias |
filamentous actin
polymeric actin |
| gptkbp:component |
cytoskeleton
|
| gptkbp:composedOf |
gptkb:G-actin
|
| gptkbp:depolymerization |
ADP-actin dissociation
|
| gptkbp:discoveredBy |
gptkb:Albert_Szent-Györgyi
|
| gptkbp:dynamic |
yes
|
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:function |
muscle contraction
cell motility cytokinesis intracellular transport cell shape maintenance |
| https://www.w3.org/2000/01/rdf-schema#label |
F-actin
|
| gptkbp:interactsWith |
gptkb:alpha-actinin
gptkb:tropomyosin gptkb:dystrophin gptkb:myosin profilin Arp2/3 complex cofilin fimbrin formin gelsolin spectrin villin |
| gptkbp:length |
variable
|
| gptkbp:location |
microvilli
cell cortex filopodia lamellipodia stress fibers |
| gptkbp:polymerization |
ATP-dependent
|
| gptkbp:regulates |
actin-binding proteins
|
| gptkbp:requires |
signal transduction
cell division cell migration cell adhesion endocytosis exocytosis mechanotransduction |
| gptkbp:stable |
phalloidin
|
| gptkbp:stainedBy |
fluorescent phalloidin derivatives
phalloidin |
| gptkbp:structure |
helical polymer
|
| gptkbp:visualizes |
fluorescence microscopy
|
| gptkbp:bfsParent |
gptkb:RAPGEF7
|
| gptkbp:bfsLayer |
7
|