Statements (50)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:cancer
Gynecologic cancer |
gptkbp:affects |
gptkb:Uterus
Endometrium |
gptkbp:associatedWith |
PTEN mutation
MLH1 mutation MSH2 mutation P53 mutation |
gptkbp:canMetastasizeTo |
gptkb:bone
Lungs Liver Lymph nodes |
gptkbp:commonIn |
Postmenopausal women
|
gptkbp:diagnosedBy |
Dilation and curettage
Endometrial biopsy Transvaginal ultrasound |
gptkbp:firstDescribed |
19th century
|
gptkbp:hasScreening |
No standard screening
|
https://www.w3.org/2000/01/rdf-schema#label |
Endometrial carcinoma
|
gptkbp:ICD-10_code |
gptkb:C54.1
|
gptkbp:incidence |
Most common gynecologic malignancy in developed countries
|
gptkbp:marking |
CA-125 (sometimes elevated)
|
gptkbp:predecessor |
Endometrial hyperplasia
|
gptkbp:prevalence |
More common in developed countries
|
gptkbp:prognosis |
Good if detected early
|
gptkbp:riskFactor |
gptkb:Lynch_syndrome
gptkb:Diabetes_mellitus gptkb:Polycystic_ovary_syndrome Obesity Hypertension Early menarche Late menopause Nulliparity Tamoxifen use Unopposed estrogen exposure |
gptkbp:stageName |
gptkb:FIGO_staging
|
gptkbp:subspecies |
gptkb:Clear_cell_carcinoma
gptkb:Endometrioid_adenocarcinoma gptkb:Serous_carcinoma |
gptkbp:symptom |
Weight loss
Abnormal uterine bleeding Pelvic pain Postmenopausal bleeding |
gptkbp:treatment |
radiation therapy
Surgery Chemotherapy Hysterectomy Hormonal therapy |
gptkbp:bfsParent |
gptkb:Uterine_cancer
|
gptkbp:bfsLayer |
7
|