|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:erythropoietin
gptkb:EP
MVCD2
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:anemia
polycythemia
|
|
gptkbp:biologicalProcess
|
hormone activity
erythrocyte differentiation
response to decreased oxygen levels
|
|
gptkbp:cellularComponent
|
extracellular region
|
|
gptkbp:discoveredBy
|
Eugene Goldwasser
|
|
gptkbp:encodes
|
gptkb:erythropoietin
|
|
gptkbp:Entrez_Gene_ID
|
2056
ENSG00000130427
|
|
gptkbp:expressedIn
|
gptkb:kidney
liver
|
|
gptkbp:firstDescribed
|
1977
|
|
gptkbp:fullName
|
gptkb:erythropoietin_gene
|
|
gptkbp:function
|
response to hypoxia
regulation of erythropoiesis
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:3416
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
EPO gene
|
|
gptkbp:locatedOnChromosome
|
7q22.1
|
|
gptkbp:mutationAssociatedWith
|
can cause anemia
can cause familial erythrocytosis
|
|
gptkbp:OMIM
|
133170
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
Mus musculus (mouse)
Rattus norvegicus (rat)
|
|
gptkbp:product
|
gptkb:erythropoietin
|
|
gptkbp:regulates
|
induced by hypoxia-inducible factor (HIF)
|
|
gptkbp:significance
|
target for anemia therapy
target for erythropoiesis-stimulating agents
|
|
gptkbp:symbol
|
gptkb:EPO
|
|
gptkbp:UniProtID
|
P01588
|
|
gptkbp:bfsParent
|
gptkb:Erythropoietin
gptkb:erythropoietin
|
|
gptkbp:bfsLayer
|
6
|