Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Ensembl gene ID
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:discoveredBy |
gptkb:Mary-Claire_King
|
| gptkbp:encodes |
gptkb:Breast_cancer_type_1_susceptibility_protein
|
| gptkbp:Entrez_Gene_ID |
672
ENSP00000350283 |
| gptkbp:gene |
gptkb:BRCA1
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:GO_term |
gptkb:nucleus
cell proliferation DNA repair regulation of cell cycle apoptotic process negative regulation of cell proliferation protein binding protein ubiquitination ubiquitin-protein transferase activity DNA binding regulation of transcription, DNA-templated cell cycle checkpoint cellular response to stress chromatin binding double-strand break repair tumor suppressor activity cellular response to DNA damage stimulus response to DNA damage stimulus chromosome organization protein complex assembly regulation of apoptotic process positive regulation of DNA repair |
| gptkbp:hasRefSeqID |
gptkb:NM_007294
|
| gptkbp:hasTranscript |
ENST00000357654
|
| gptkbp:HGNC_ID |
HGNC:1100
|
| https://www.w3.org/2000/01/rdf-schema#label |
ENSG00000125691
|
| gptkbp:isTumorSuppressor |
true
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_17
43044295 43125482 |
| gptkbp:OMIM |
113705
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
gptkb:1JM7
gptkb:1T15 1JLN 1JNX 1N50 |
| gptkbp:strand |
minus
|
| gptkbp:UniProtID |
P38398
|
| gptkbp:bfsParent |
gptkb:GKLF
|
| gptkbp:bfsLayer |
7
|