EMT (epithelial-mesenchymal transition)
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:abbreviation |
epithelial-mesenchymal transition
|
| gptkbp:associatedWith |
metastasis
fibrosis |
| gptkbp:characterizedBy |
increased cell motility
loss of cell-cell adhesion |
| gptkbp:designer |
mesenchymal-epithelial transition (MET)
|
| gptkbp:fullName |
epithelial-mesenchymal transition
|
| https://www.w3.org/2000/01/rdf-schema#label |
EMT (epithelial-mesenchymal transition)
|
| gptkbp:involves |
gain of mesenchymal traits
loss of epithelial characteristics |
| gptkbp:marking |
decreased E-cadherin
increased N-cadherin increased fibronectin increased vimentin |
| gptkbp:occurredIn |
embryonic development
wound healing cancer progression |
| gptkbp:regulates |
gptkb:Notch_signaling_pathway
gptkb:Wnt_signaling_pathway TGF-beta signaling Snail transcription factor Twist transcription factor ZEB transcription factors |
| gptkbp:studiedIn |
cancer research
developmental biology |
| gptkbp:bfsParent |
gptkb:SNAI1
gptkb:Brachyury_gene |
| gptkbp:bfsLayer |
7
|