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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alternativeName
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gptkb:EF-Tu
Translation elongation factor Tu
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gptkbp:binds
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gptkb:GDP
gptkb:GTP
gptkb:aminoacyl-tRNA
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gptkbp:conservedIn
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highly conserved among bacteria
|
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gptkbp:discoveredBy
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gptkb:Masayasu_Nomura
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gptkbp:discoveredIn
|
1960s
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gptkbp:EC_number
|
3.6.5.3
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gptkbp:encodedBy
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gptkb:tuf_gene
|
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gptkbp:fullName
|
gptkb:Elongation_factor_thermo_unstable
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gptkbp:function
|
delivers aminoacyl-tRNA to the ribosome
GTPase involved in protein synthesis
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gptkbp:gene
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gptkb:tufA
gptkb:tufB
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gptkbp:GO
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GO:0003746
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gptkbp:inhibitedBy
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gptkb:pulvomycin
gptkb:enacyloxin_IIa
gptkb:kirromycin
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gptkbp:interactsWith
|
ribosome
EF-Ts
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gptkbp:locale
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gptkb:cytoplasm
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gptkbp:molecularWeight
|
~43 kDa
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gptkbp:mutationAssociatedWith
|
lethal in E. coli
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gptkbp:organism
|
gptkb:Bacteria
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gptkbp:orthologIn
|
aEF1A (archaea)
eEF1A (eukaryotes)
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gptkbp:PDB
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gptkb:1EFC
1TTT
|
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gptkbp:postTranslationalModification
|
phosphorylation
methylation
lysine acetylation
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gptkbp:presentIn
|
gptkb:Mycobacterium_tuberculosis
gptkb:Bacteria
gptkb:Bacillus_subtilis
many bacteria
|
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gptkbp:recycledBy
|
EF-Ts
|
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gptkbp:releaseYear
|
GTP hydrolysis
|
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gptkbp:requires
|
cell viability in bacteria
|
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gptkbp:role
|
translation elongation
accuracy of protein synthesis
|
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gptkbp:structure
|
contains GTP-binding domain
composed of three domains
|
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gptkbp:UniProtID
|
gptkb:P0A6F5
|
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gptkbp:bfsParent
|
gptkb:tufA
gptkb:tufB
gptkb:tuf_gene
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gptkbp:bfsLayer
|
8
|
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https://www.w3.org/2000/01/rdf-schema#label
|
EF-Tu protein
|