Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:catalyzes |
hydroxylation of steroids at the 6beta position
|
| gptkbp:cofactor |
NADPH
heme-thiolate (P-450) |
| gptkbp:EC_number |
1.14.14.6
|
| gptkbp:enzymeClassification |
oxidoreductase
|
| gptkbp:foundIn |
mammals
liver |
| gptkbp:GO_term |
GO:0015034
|
| https://www.w3.org/2000/01/rdf-schema#label |
EC 1.14.14.6
|
| gptkbp:otherName |
steroid 6-beta-monooxygenase
steroid 6beta-hydroxylase |
| gptkbp:part_of |
gptkb:protein
|
| gptkbp:product |
6beta-hydroxysteroids
|
| gptkbp:requires |
oxygen
|
| gptkbp:substrate |
steroids
|
| gptkbp:systematicName |
steroid,NADPH:oxygen oxidoreductase (6beta-hydroxylating)
|
| gptkbp:type |
steroid + NADPH + H+ + O2 → 6beta-hydroxysteroid + NADP+ + H2O
|
| gptkbp:UniProtID |
NADP
Heme Monooxygenase |
| gptkbp:bfsParent |
gptkb:CYP2A6
|
| gptkbp:bfsLayer |
6
|