|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:SLC1A2
|
|
gptkbp:encodedBy
|
gptkb:SLC1A2
|
|
gptkbp:Entrez_Gene_ID
|
6506
|
|
gptkbp:expressedIn
|
gptkb:spinal_cord
brain
central nervous system
astrocytes
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:fullName
|
Excitatory amino acid transporter 2
|
|
gptkbp:function
|
glutamate transporter
|
|
gptkbp:HGNC_ID
|
10940
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
EAAT2
|
|
gptkbp:inhibitedBy
|
L-trans-pyrrolidine-2,4-dicarboxylate
dihydrokainic acid
|
|
gptkbp:locatedOnChromosome
|
11p13-p12
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
62 kDa
|
|
gptkbp:mutationAssociatedWith
|
amyotrophic lateral sclerosis
|
|
gptkbp:OMIM
|
600300
|
|
gptkbp:orthologIn
|
gptkb:mouse
right
|
|
gptkbp:prevention
|
excitotoxicity
|
|
gptkbp:regulates
|
transcription factors
epigenetic mechanisms
|
|
gptkbp:removes
|
glutamate from synaptic cleft
|
|
gptkbp:structureType
|
transmembrane protein
|
|
gptkbp:transmembraneDomains
|
8
|
|
gptkbp:transporterFamily
|
gptkb:SLC1_family
|
|
gptkbp:UniProtID
|
P43004
|
|
gptkbp:bfsParent
|
gptkb:SLC1A2
|
|
gptkbp:bfsLayer
|
7
|